Dr. Yiğit Altay
Senior Scientist
Mosa Meat B.V.
Watermolen 28,
6229 PM Maastricht,
The Netherlands
Languages
Turkish
English
Dutch
Technical Skills
Liquid Chromatography
Mass Spectrometry

LC-MS, GC-MS, ESI and MALDI

Solid State Peptide Synthesis
Omics Suite

Proteomics, metabolomics and lipidomics

Spectroscopy (others)

Circular Dichroism, Fluorescence, UV-Vis, Infrared

Organic Synthesis
NMR Spectroscopy
Microscopy

Optical, Confocal, SEM, TEM

Single Crystal XRD
Programming Languages
HTML

HTML5 , CSS3

PhP
Python
Processing
Matlab
ASP.NET
Java
Computer Programs
Microsoft Office

Word, Excel, Powerpoint, Outlook, Access

iWork Suite

Keynote, Pages, Numbers

Adobe Suite

Photoshop, Illustrator, InDesign. Dreamviewer

Autodesk Suite

3Ds Max

Latex
Origin
Berkeley Madonna

I am a chemist specialised in analysis of complex molecular networks. I have conducted research in the field between chemistry and biology with a focus on supramolecular and systems chemistry. Primary areas of interest include artificial life, out-of-equilibrium systems, self-replication, self-assembly of macromolecules, catalytic activity of peptides, fluorescent molecular recognition systems, analysis of cultured meat using omic approaches. 

ORCID iD iconorcid.org/0000-0002-3413-9030

Work
Senior Scientist
Mosa Meat B.V.Dec 2020 - Present

Leading the analytical activities for novel food application, developing analytical methods for fresh and spent cell culture media and cell-cultured tissues, developing multi-omic aproaches for cultured meat.

Postdoctoral Research Fellow
Eindhoven University of TechnologyNov 2018- Oct 2020
Doctorate of Philosopy, PhD
University of GroningenSept 2013- Aug 2017
Education
2013 - 2017
University of Groningen, Stratingh Institute for ChemistryGroningen, the Netherlands

Philosophy of Doctorate (PhD).

2011 - 2013
Bilkent University, Department of ChemistryAnkara, Turkey

Master of Science (MSc), CUMGPA: 3.84 / 4.00.

2010
Eindhoven University of Technology, Department of ChemistryEindhoven, the Netherlands

Erasmus exchange student.

2006 - 2011
Bilkent University, Department of ChemistryAnkara, Turkey

Bachelor in Science (BSc). Graduated cum laude, CUMGPA: 3.71 / 4.00

2002-2006
Yildirim Beyazit Anatolian High SchoolAnkara, Turkey

Graduation grade: 5.00/5.00

Publications

10. Yigit Altay, Antoni Llopis-Lorente, Loai K.E.A. Abdelmohsen, and Jan C.M. van Hest, "Chemical Cascading Between Polymersomal Nanoreactor Populations", manuscript submitted.

9. Joydev Hatai, Yigit Altay, Ankush Sood, Armin Kiani, Marcel Eleveld, Leila Motiei, David MarguliesSijbren Otto, "An Optical Probe for Real-Time Monitoring of Self-Replicator Emergence and Distinguishing between Replicators", JACS 2022, 144, 3074–3082. DOI:  10.1021/jacs.1c11594.

Highlighted in JACS Spotlight by Kimberly Bolduc.

8. Yigit Altay, Imke A. B. Pijpers, Loai K. E. Abdelmohsen and Jan C. M. van Hest, "Dynamic Assembly of Micellar Meso-structures", ChemSystemsChem 2019, 1, e190004. DOI: 10.1002/syst.201900049.

7. Yigit Altay, Shoupeng Cao, Hailong Che, Loai K. E. Abdelmohsen and Jan C. M. van Hest, "Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine", Biomacromolecules 2019, 20 (11), 4053-4064. DOI: 10.1021/acs.biomac.9b01341

6.  Yigit Altay Meniz Altay and Sijbren Otto, “Existing Self‐Replicators Can Direct the Emergence of New Ones”,Chem. Eur. J. 2018, 24, 11911 – 11915. DOI: 10.1002/chem.201803027 . 

5. Meniz Altay, Yigit Altay and Sijbren Otto, “Parasitic Behavior of Self‐Replicating Molecules”, Angew. Chem. Int. Ed., 2018,  139 (57), pp 10564–10568. DOI: 10.1002/anie.201804706

Highlighted in chemistryworld.com by James Urquhart (June 26, 2018)

4. Yigit Altay, Meniz Tezcan and Sijbren Otto, “Emergence of a New Self-Replicator from a Dynamic Combinatorial Library Requires a Specific Pre-Existing Replicator”, JACS, 2017,  139 (39), pp 13612–13615. DOI: 10.1021/jacs.7b07346  

3. Pim W. J. M. Frederix, Julien Idé, Yigit Altay, Gaël Schaeffer, Mathieu Surin, David Beljonne, Anna S. Bondarenko, Thomas L. C. Jansen, Sijbren Otto, and Siewert J. Marrink, “Structural and Spectroscopic Properties of Assemblies of Self-Replicating Peptide Macrocycles”, ACS Nano, 2017, 11 (8), pp 7858-7868. DOI: 10.1021/acsnano.7b02211

2. Murat Işık, Ruslan Guliyev, Safacan Kölemen, Yigit Altay, and Engin U. Akkaya, “Selective Sensing in Space and Time: Designing Kinetic and Thermodynamic Differentiation for Biologically Relevant Thiols”, Org. Lett., 2014, 16 (12), 3260-3263. DOI: 10.1021/ol501272z

1. Safacan Kolemen, Yusuf Cakmak, Sule Erten-Ela, Yigit Altay, Johannes Brendel, Mukundan Thelakkat, and Engin U. Akkaya. , “Solid State Dye-Sensitized Solar Cells Using Red and Near IR Absorbing Bodipy Sensitizers”, Org. Lett., 2010, 12 (17), 3812-3815. DOI: 10.1021/ol1014762 

 

Project Experience
2013 - Present
System Chemistry Lab – Prof. Sijbren OttoGroningen, the Netherlands
  • “Search for larger self-replicators from dynamic combinatorial libraries”
  • “Template assisted emergence of novel replicators”
  • "Spectroscopic studies of self-replicators"
  • "Salt effects in self-replication kinetics"
  • "History dependence of dynamic combinatorial libraries in out-of-equilibrium conditions"
  • "Sustainability of self-replicators at far-from-equilibrium"
2011 - 2013
Supramolecular Chemistry Laboratory - Prof. Engin Umut AkkayaAnkara, Turkey
  • “A Homogeneous System for Photogeneration of Hydrogen from BODIPY Based Photoinduced Electron Transfer System”
  • “Nanovesicle formation and catalytic activity of short peptide amphiphiles: Implications on the origin of life.”
  • “Strengthening of self-assembled amphiphilic peptide nanotubes through controlled click chemistry. ”
  • “Selective Fluorescence Sensing of Biological Thiols Using a BODIPY based Bifunctional Probe.”
  • “Enantioselective Sensing of Amino Acids by Atropisomeric BODIPY Dyes.”
2010
Laboratory of Macromolecular and Organic Chemistry – Prof. Rint P. SijbesmaEindhoven, the Netherlands
  • “Study of poly(2-hydroxylethylmethacrylate) based hydrogel beads under swelling and contraction conditions by fluorescence resonance energy transfer”
2011 - 2013
Supramolecular Chemistry Laboratory - Prof. Engin Umut AkkayaAnkara, Turkey
  • “Modulation of excited energy transfer through PET mechanism in dendritic systems”
  • “Synthesis of Bodipy dyes for solid state dye-sensitized solar cells using red and near IR absorbing Bodipy sensitizers”
  • “Chemiluminescence activation of a photosensitizer through energy transfer”
2008
TUBITAK Hydromobile Hydrogen Car RacingAnkara, Turkey
  • Bilkent University Team
Teaching Experience
2013 - 2017
University of Groningen, Stratingh Institute for ChemistryGroningen, the Netherlands

Synthesis and Analysis I practical course supervisor.

2011 - 2013
Bilkent University, Department of ChemistryAnkara, Turkey

Organic Chemistry I and II laboratory supervisor

2010
Turkish Aerospace Industries, Inc. (TAI)Ankara, Turkey

Summer internship at fresh water, domestic/ industrial waste purification facilities.

Conferences and Meetings:
2016, August 31 - September 2
ERC Grantees ConferenceZandvoort, the Netherlands

Poster Presentation

2015, November 29
Functional Molecular Materials (FMS) Annual MeetingVeldhoven, the Netherlands

Oral Presentation

2015, June 10 - 12
Stratingh Institute WorkweekEindhoven, the Netherlands

Organization Committee and Poster Presentation

2015, May 27
Dutch Peptide SymposiumNijmegen, The Netherlands

Poster Presentation

2015, May 19 - 22
SysChem 2015Kerkrade, the Netherlands

Organization Committee and Poster Presentation

2015, April 14
UTwente – RuG Joint SymposiumGroningen, the Netherlands

Poster Presentation

2014, November 17-19
CHAINS: Dutch National Chemistry ConferenceVeldhoven, the Netherlands

Poster Presentation

2014, September 8 - 12
Summer School: Challenges in Supramolecular ChemistryStrasbourg, France

Flash and Poster Presentation

2014, June 4 - 6
Stratingh Institute WorkweekHeidelberg, Germany

Poster Presentation

2014, May 13
Dutch Peptide SymposiumUtrecth, the Netherlands

Participant

2014, February 2 - 7
e-WISPOC European Winter School on Physical Organic ChemistryBressanone, Italy

Poster Presentation

2013, December 16 - 18
RSC Macrocyclic and Supramolecular Chemistry MeetingGlasgow, United Kingdom

Poster Presentation

2013, September 11 - 12
Centre for Systems Chemistry SymposiumGroningen, the Netherlands

Participant

2013, June 30 – July 5
63rd Lindau Nobel Laureate MeetingLindau, Germany

Participant (Selected among 40.000 applications). Supported by TUBITAK.

2012, October 1 - 6
26rd Turkish National Chemistry CongressMugla, Turkey

Poster Presentation

2011, July 3 - 7
6th International Symposium on Macrocyclic & Supramolecular ChemistryBrighton, United Kingdom

Poster Presentation

2011, June 14 - 17
2nd National Chemistry Students CongressBolu, Turkey

Oral Presentation

2010, October 22 - 25
Molecular Sensors and Logic Gates ConferenceAntalya, Turkey

Organising Committee.

2010, September 30 - October 6
SCAN 2010 Workshop and School “Synthesis, Characterization and Applications of Nanomaterials”Ankara, Turkey

Participant.

2008
Symposium on Surface ScienceAnkara, Turkey

Participant.

2007
National Nanotechnology ConferenceAnkara, Turkey

Participant.

2007
Technical Calculations with MATLAB SeminarAnkara, Turkey

Participant.

Awards and Certificates
Summer School: Challenges in Supramolecular Chemistry
2014 - The Best Flash Presentation awardStrasbourg, France
63rd Lindau Nobel Laureate Meeting
2013 - Participation CertificateLindau, Germany
Bilkent University, Department of Chemistry
2011 - Full Scholarship for Graduate StudentsAnkara, Turkey
II. National Chemistry Student Congress
2011 - The Best Oral Presentation AwardBolu, Turkey
TUBITAK
2010 - Grant for Undergraduate Students National/International Research ProjectsAnkara, Turkey
Bilkent University, Department of Chemistry
2006 - Full Scholarship for Undergraduate studentsAnkara, Turkey
Bilkent University, Department of Chemistry
2006-2011 - High Honor & Honor CertificatesAnkara, Turkey
Yıldırım Beyazıt Anatolian High School
2002-2006 - High Honor CertificatesAnkara, Turkey
Memberships
2009 - Present
American Chemical Society
2013 - Present
Oriental Numismatic Society
2009 - Present
Izmir Numismatic Society
2008 - Present
The Cloud Appreciation Society
2010 - 2011
Founder Member and the President of the Bilkent Chemistry Club
2006 - 2011
Board Member, Photographer, Illustrator and designer of Bilkent Koza Magazine
Interests and Activities

Coin Collection:

References

References and letters of recommendation are available on request.